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New CFS Study Published August 2016 –  Robert Naviaux and Gordon Medical : “Metabolic features of chronic fatigue syndrome” – 2016

See more on the study…

Evidence that CFS truly does deserve all three elements of its name has accumulated over the years but a definitive diagnostic test has remained elusive. Until, perhaps, now. For in this week’s Proceedings of the National Academy of Sciences Robert Naviaux of the University of California, San Diego, and his colleagues published evidence that the metabolisms of those diagnosed with CFS are all changing in the same way. Their data suggest it is this cellular response to CFS-triggering traumas, and not the way the response is set in motion, which should define the illness. They also show that this response produces a chemical signal that might be used for diagnosis.

The Economist

Gordon Medical Research Center (GMRC) is organizing a new community sponsored research study to investigate how individual metabolomic data can be used to evaluate CFS/ME.

This will be the third study organized by GMRC researching how comprehensive metabolomic analysis can be used to evaluate CFS/ME. This study follows our first study (see above), conducted in collaboration with UC San Diego and recently published in the Proceedings of the National Academy of Science, which demonstrated there is a clear metabolomic profile in patients with CFS/ME; and our second North American based CFS/ME study, which has finished enrolling patients and will be completed soon, also in collaboration with UC San Diego.

This third study will be the first to look at how individual as opposed to population based metabolomics data can be used to evaluate CFS/ME. GMRC’s third CFS/ME research study will be a community-sponsored investigation. The CFS/ME community is a highly motivated group and we will need their support to accomplish our goal of understanding how personal metabolomic data can be used to evaluate CFS/ME.

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Members of the CFS/ME community and their advocates can contribute to the success of the study in three main ways:

  1. They can participate in the study by volunteering a blood sample. – PARTICIPATE
  2. They can recruit a person without a diagnosis of CFS/ME to donate a blood sample that will serve as a comparison sample.
  3. Members of the community can make a tax-deductible donation to fund the study. – DONATE


All donations are welcome, and donations to this third metabolomic study will go to sample collection, metabolomic data generation, and development of CFS/ME-specific analysis software.

For a donation of $1500 or more, individuals will receive a Personal Metabolomic Assessment (PMA) report that will show them how their metabolomic profile compares to a healthy population and the overall CFS population. Included in the >500 metabolites in this report will be analysis of sphingomyelin metabolites which were shown to be of interest to the CFS/ME community in our first study. This is the ONLY metabolomic report currently capable of providing data on this critical class of molecules.

We look forwarded to working with the CFS/ME patient community and their supporters to make this unique community-sponsored research study a success.

We have collected 12.07% of our $400,000.00 target for the Metabolomics in CFS/ME.


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